Laboratory of Immunophysiology
Our lab aims to investigate the development, trajectory, biology and functions of myeloid cells in health and disease, with a particular interest in the lung mucosa and in lung chronic inflammatory disorders.
Our lab aims to investigate the development, trajectory, biology and functions of myeloid cells in health and disease, with a particular interest in the lung mucosa and in lung chronic inflammatory disorders.
This prestigious scientific award, presented in the presence of HM the Queen, will help fund his research on respiratory physiology, particularly the role of pulmonary neutrophils.
A study led by Thomas Marichal's team reveals how signals from endothelial cells lining blood vessels guide the development of interstitial macrophages — immune cells essential for maintaining lung tissue integrity.
A recently identified population of macrophages has been found to play a crucial role in alveolar regeneration, with the potential to reduce complications from severe respiratory infections and Acute Respiratory Distress Syndrome (ARDS).
Discover the research topics addressed in the laboratory of Immunophysiology (GIGA-I3).
Monocyte-to-Macrophage Trajectories After Lung Injury: Spatio-temporal investigation, molecular regulation & functional implications for lung regeneration and immunity
Deciphering the contribution of the myeloid-epithelial crosstalk to viral-induced exacerbations of chronic airway diseases: an inescapable path towards precision medicine and improved quality of life
Recruited atypical Ly6G+ macrophages license alveolar regeneration after lung injury in Science Immunology. Free-access reprint link to the paper: https://www.science.org/stoken/author-tokens/ST-2022/full
Atypical myeloid cells emerging during the recovery phase of respiratory viral infections: origin, identity, functions and regulation by tissue cues, host risk factors and chronic stress.
Welbio & F.R.S.-FNRS Permanent Investigator
Immunophysiology Lab
GIGA-Research B34, University of Liege,
Quartier HOPITAL
Avenue de l’Hôpital, 11, 4000 Liège
t.marichal@uliege.be
+ 32 4 366 95 55